6-Demethyl-6-deoxytetracycline; GS 2147
808-26-4
414.4
C21H22N2O7
DMSO
-20°C
Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin, first reported in 1962. As the simplest of the early tetracyclines, sancycline was the first to be totally synthesised by Conover and co-workers. Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
